CDH1 DNA Phylogeny
Phylogentic tree generated using TreeFam
Analysis
The phylogenetic tree above contains all Euteleostomi homologs of CDH1. Human CDH1 is termed CDH1_F3_HUMAN and is highlighted in red. The Euteleostomi clade contains over 90% of vertebrate. It appears that CDH1 is closely related to CDH3. CDH3 codes for P-Cadherin, which is also a member of the Cadherin Superfamily. CDH1 in humans seems to be well conserved in mice, making it a potentially powerful model to study CDH1 and its role in disease.